On Tuesday, September 8, 2026, a comprehensive scientific study titled “Tracing the evolution and diversity of human parvovirus B19 across human history” was published in the renowned scientific journal Current Biology.
Dr. Mario Novak, Senior Research Associate from the Zagreb Institute for Anthropological Research, participated as a co-author in this significant international study, which yields new insights into the origin, diversity, and long evolutionary history of human parvovirus B19.
Understanding Viral History Through Ancient DNA
Human parvovirus B19 is a widespread pathogen known for causing “fifth disease” (erythema infectiosum) in children, while potentially triggering more severe health complications in adults and individuals with compromised immune systems or hematological disorders.
The research team used state-of-the-art ancient DNA (aDNA) analysis techniques to trace the genetic development of the virus across various historical and prehistoric periods. By reconstructing viral genomes from archaeological remains, scientists succeeded in illuminating how parvovirus B19 evolved over millennia, how its distinct genetic lineages emerged, and how its evolution interacted with human population migrations and demographic shifts.
Contribution of Croatian Bioarchaeology
The participation of Dr. Mario Novak from the Institute for Anthropological Research underscores the important role of Croatian bioarchaeologists and anthropologists in major global interdisciplinary projects combining archaeology, genetics, and paleopathology. Studying ancient pathogens like parvovirus B19 provides insights into the health conditions and afflictions of our ancestors while helping researchers better comprehend the dynamics and evolutionary adaptability of modern infectious diseases.
The full paper, including detailed methodology, sample analyses, and findings, is accessible to the public and scientific community on the journal’s official website:
https://www.sciencedirect.com/science/article/pii/S0960982226010833
