Contact: iris.car@inantro.hr, iris.car@student.uniri.hr

Achieved education, academic and scientific degrees

  • 2019. – PhD programme “Medicinal chemistry” Department of Biotechnology, University of Rijeka
  • 2016.-2019.  Graduate programme “Biotechnology in medicine” Department of Biotechnology, University of Rijeka
  • 2013.-2016. Undergraduate programme “Biotechnology and drug research” Department of Biotechnology, University of Rijeka

Work experience

  • 2021.- Assistant, Institute for Anthropological research, Center for Applied Bioanthropology
  • 2019.-2021. Assistant, Department of Biotechnology, University of Rijeka

Participation in projects

Croatian Science Foundation – “Rasvjetljavanje mehanizama rezistencije na terapiju raka debelog crijeva sa mutacijom BRAF pomoću integriranog  -omics pristupa (BRAFCON)”, PI dr.sc. Mirela Sedić

Participation in scientific conferences

  • EMBO Workshop – Systems approaches in cancer; Split 21/09/2021-26/09/2021; poster presentation „Proteomics complemented with bioinformatics analysis identified the importance of actin cytoskeleton and extracellular matrix organization as well as caveolae-associated functions in the resistance mechanisms to vemurafenib in BRAFV600E mutated RKO colon cancer cells“ authors: Iris Car, Antje Dittmann, Petra Grbčić, Marko Klobučar, Luka Bočkor, Olga Vasieva, Sandra Kraljević Pavelić, Mirela Sedić
  • 8th Annual Congress of the European Society for Translational Medicine, virtual, 20/09/2021-26/09/2021; poster presentation „Proteomic and N-glycome profiling of secretome from BRAFV600E mutant colon cancer cells with acquired resistance to vemurafenib“; authors: I. Car, M. Klobučar, A. Dittmann, O. Vasieva, P. Grbčić, S. Kraljević Pavelić, M. Sedić
  • 27th Congress of the European Association for Cancer Research, virtual, 09/06/2021 – 12/06/2021; poster presentation „Integrated proteomics and bioinformatics approach reveals caveolae-associated signaling as novel druggable vulnerability of vemurafenib-resistant colon cancer cells with BRAFV600E mutation“; authors: M. Sedić, I. Car, A. Dittmann, O. Vasieva, P. Grbčić, M. Klobučar, S. Kraljević Pavelić
  • Alps-Adriatic Rectors’ Conference, Rijeka, 19/09/2019 – 20/09/2019; poster and oral presentation „Secretome analysis of BRAF V600E-mutant colon cancer cells with acquired resistance to vemurafenib“; authors: I. Car, M. Klobučar, S. Kraljević Pavelić, M. Sedić
  • 15th Central European Oncology Congress – A Best of ASCO Meeting, Opatija, 26/06/2019 – 29/06/2019; Best poster award, poster presentation „Proteomic profiling of BRAF V600E-mutant colon cancer cells with acquired resistance to vemurafenib“; authors: I. Car, M. Klobučar, S. Kraljević Pavelić, M. Sedić
  • 13th Mass spectrometry in Biotechnology and Medicine, Dubrovnik, 07/07/2019 – 13/07/2019; poster presentation „Optimization of protocol for secretome collection from vemurafenib-resistant BRAFV600E mutant colon cancer cells for mass spectrometry-based proteome analysis“ ; authors: I. Car, M. Klobučar, S. Kraljević Pavelić, M. Sedić

List of publications

  1. Different expression of lumican glycoforms in non-metastatic and metastatic laryngeal squamous cell carcinoma; autori: Car, I., Visentin, S., Đanić, D., Klobučar, M.; Publication date 01.03.2021.; Journal Medicina Fluminensis: Medicina Fluminensis; Volume 57; Issue 1; Pages 114-121; DOI: https://doi.org/10.21860/medflum2021_365329
  2. Mass spectrometry-based glycomic profiling of the total IgG and total proteome N-glycomes isolated from follicular fluid; autori: Klobučar, M., Dević Pavlić, S., Car, I., Smiljan Severinski, N, Tramišak Milaković, T., Radojčić Badovinac, A., Kraljević Pavelić, S.; Biomolecular Concepts, Publication date: 25.10.2020.; Volume 11, Issue 1, Pages 153-171, Publisher; De Gruyter, DOI: https://doi.org/10.1515/bmc-2020-0015.
  3. N-glycans as Biomarkers in Chronic Disease; autori: Car, I., Klobučar, M.; poglavlje u knjizi „Novel Perspectives in Economics of Personalized Medicine and Healthcare Systems“, Publisher: NOVA Science Publishers, Hauppauge, NY, 11788 USA; Publication Date: December 17, 2021.; DOI: https://doi.org/10.52305/IMRM1661.

 Memberships

  • Croatian Society of Biochemistry and Molecular Biology; member since 2022.
  • Croatian society for proteomics and metabolomics; member since 2021.