A scientific paper entitled “The Sphingosine Kinase 2 Inhibitor ABC294640 Restores the Sensitivity of BRAFV600E Mutant Colon Cancer Cells to Vemurafenib by Reducing AKT-Mediated Expression of Nucleophosmin and Translationally-Controlled Tumor Protein” was published in the International Journal of Molecular Sciences. Mirela Sedić, PhD, one of the authors of the paper, is from the Institute for Anthropological Research. This paper is the result of scientific research conducted within the project HRZZ IP-2018-01-3900 led by M. Sedić.

Access to paper via the following link: https://www.mdpi.com/1422-0067/22/19/10767/htm

Individualized approach in the prediction of type 2 diabetes onset and development (IRI) (KK.01.2.1.02)

New project is funded by European Fund for Regional Development (KK.01.2.1.02) in period from 17. 08. 2020 till 17. 08. 2023.

Our associates are Medilab ONE and Genos. Associates from Institute for Anthropological Research are Saša Missoni, PhD, Vedrana Škaro, PhD, and Petar Projić, PhD.

The project is an industrial research aimed at developing an individualized screening service for high-risk patients, based on the plasma glycome. The final product will be a developed test with identified molecular structures that suggest the development of type 2 diabetes in patients with no signs of the disease. This product will predict the time period in which diabetes will develop from a pre-diabetes stage, and will include recommendations of “lifestyle habits” that permanently or temporarily delay the disease onset and development (dietary habits – preferably based on menus developed individually according to the metabolic characteristics of high-risk patients and physical activity/exercise). Through this project, glycan and protein biomarkers for the development of type 2 diabetes and the impact of lifestyle habits on the prolongation of the period in which the disease occurs will be investigated.

The pandemic has spurred much research into the new disease. Thus, the Institute has been involved in various ways in research and as an aid to other institutions in the form of lending devices and collaboration of scientists.

One of the research will be a project Unravelling Data for Rapid Evidence-Based Response to COVID-19 (unCoVer) gained through H2020-SC1-PHE-CORONAVIRUS-2020-2-RTD.

Project duration 15th november 2020 – 14th november 2022.

More info on https://inantro.hr/en/homepage-eng/projects/international-projects/

Tracing the Slavic origins of Croatians using ancient genomes and Reconstruction of genetic diversity and migratory patterns of late Avar population using ancient DNA analysis are both funded by Austrian Academy of Science, JESH programme.

Duration of them is from 2021 to 2022.

More info on https://inantro.hr/en/homepage-eng/projects/international-projects/

Institute for Anthropological Research in Zagreb, Croatia has just started a new scientific journal that you may find of interest.

Journal of Bioanthropology covers a broad field of bioanthropological research and it would be our pleasure if you would consider publishing your research in it.

More on journal: https://inantro.hr/en/journal-of-bioanthropology-2/

Journal of Bioanthropology

On Wednesday, March 10th 2021, paleogenetic study of the victims of the Copper Age massacre from Potočani near Požega titled „Genome-wide analysis of nearly all the victims of a 6200 year old massacre“ was published in scientific journal PLOS ONE. Dr. Mario Novak and Dr. Ivor Janković from the Centre for Applied Bioanthropology of the Institute for Anthropological Research participated and co-authored the study. This study generated huge interest in Croatian and international media.

Original article

On October 15^th and 16^th 2020, the first Management Committee meeting of the COST Action Integrating Neandertal Legacy: From Past to Present – iNEAL (no. 19141) was held. These dates also marked an official start of the project, which will be implemented during 4 years. The main proposer and chair of the Action is Prof. Ivor Janković, PhD, from the Institute for Anthropological Research, Zagreb, Croatia. Current number of countries involved is 25. One of the main principles of COST Actions is openness, so it is envisaged that more countries will be involved during the course of the Action. This is sixth COST Action that is granted and lead by a Croatian researcher.

During the four years, numerous work meetings will be organized, as well as Working Group meetings, training schools and short-term scientific missions which will especially address young researchers. Besides the establishment of the database about Neandertals from three aspects (fossil, cultural and molecular), special attention will be given to dissemination and presentation of Neandertal legacy in public.

CRIBS PROJECT PUBLISHED IN PRESTIGIOUS NUTRIENTS MAGAZINE

In July 2020, the international journal Nutrients (Q1, Impact factor 4,546) published a paper on the Mediterranean diet and lifestyle of pregnant women and the observed differences between the mainland and the island part of Dalmatia. The paper is based on the results of the Croatian Science Foundation’s scientific project “Cohort Study of Those Born in the Eastern Adriatic Islands (CRIBS)”, and the authors are associates from the Institute for Anthropological research (Saša Missoni, PhD; Dubravka Havaš Auguštin, PhD; Jelena Šarac,PhD; Natalija Novokmet, PhD and Nives Fuchs and colleagues from the Srebrnjak Children ‘s Hospital.

Abstract and more information

Dr.sc. Mario Novak published a new article in Science: ‘Origins and genetic legacy of prehistoric dogs’

https://science.sciencemag.org/content/370/6516/557.full